1. Kuo YZ (郭怡孜)Fang WY(方偉宇), Huang CC, Tsai ST, Wang YC, Yang CL(楊智利)Wu LW. (2017 Feb) Hyaluronan synthase 3 mediated oncogenic action through forming inter-regulation loop with tumor necrosis factor alpha in oral cancer. Oncotarget. 8(9):15563-15583.
  2. Lee MH, Shih YH, Lin SR, Chang JY(張景雲), Lin YH(林鈺皓), Sze CI, Kuo YM, Chang NS (2017) Zfra restores memory deficits in Alzheimer’s disease triple transgenic mice by blocking aggregation of TRAPPC6AΔ, SH3GLB2, tau and amyloid β and inflammatory NF-κB activation. Alzheimer's & Dementia: Translational Research & Clinical Interventions, 3, 189-204.
  3. Hsu LJ, Hong Q, Chen ST, Kuo HL(郭湘鈴), Schultz L, Heath J, Lin SR, Lee MH, Li DZ, Li ZL, Cheng HC, Armand G and Chang NS. (2017) Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed. Oncotarget 8, 19137-19155


  1. Wei-Hsuan Yen(顏薇軒)Wu-Sian Ke(柯武賢), Jan-Jong Hung, Tsung-Ming Chen(陳琮明)Jia-Shing Chen(陳嘉興)H. Sunny Sun* (2016 Jan. 14) Sp1-mediated ectopic expression of T-cell lymphoma invasion and metastasis 2 in hepatocellular carcinoma Cancer Medicine. 5(3):465-77, Impact factor 2.915, Ranking 107/213 (50.2%)
  2. Cheng CW, Hsiao JR, Fan CC, Lo YK, Tzen CY, Wu LWFang WY (方偉宇), Cheng AJ, Chen CH, Chang IS, Jiang SS, Chang JY, Lee AY. (2016 May) Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma. Mol Carcinog. 55(5):499-513.
  3. Lai TY(賴泰佑), Yen CJ, Tsai HW, Yang YS(楊郁珊)Hong WF(洪威甫)Chiang CW (2016 Jan. 26) The B56γ3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1 Oncotarget.7(4):4542-58, Impact factor 6.356, Ranking 9.95%(21/211 in Oncology)
  4. Chang NS (2016) Bubbling cell death: a hot air balloonreleased from the nucleus in the cold. Exp Biol Med(Maywood). 241, 1306-1315 (Invited peer review)
  5. Huang SS(黃聖翔), Su WP(蘇婉佩), Lin HP(林欣屏), Kuo HL(郭湘鈴), Wei HL and Chang NS. (2016) Role of WW Domain-containing Oxidoreductase WWOX in Driving T Cell Acute Lymphoblastic Leukemia Maturation. J. Biol. Chem. 291, 17319-17331
  6. Su WP(蘇婉佩), Wang WJ, Sze CI, Chang NS (2016) Zfra induction of memory anticancer response via a novel immune cell. Oncoimmunology 5, 9.
  7. Hsu LJ, Chiang MF, Sze CI, Su WP(蘇婉佩), Yap YV(葉綺雯), Lee IT, Kuo HL(郭湘鈴),Chang NS (2016) Membrane hyaluronidase HYAL-2 in WWOX and SMAD signaling. Front Cell Dev Biol. 4, 141.


  1. Wei-Yu Fang (方偉宇)Yi-Wen Chen (陳怡雯), Jenn-Ren Hsiao, Chiang-Shin Liu, Yi-Zih Kuo (郭怡孜), Yi-Ching Wang, Kung-Chao Chang, Sen-Tien Tsai, Mei-Zhu Chang, Siao-Han Lin, and Wu LW. (2015 Sept). Elevated S100A9 expression in tumor stroma functions as an early recurrence marker for early-stage oral cancer patients through increased tumor cell invasion, angiogenesis, macrophage recruitment and interleukin-6 production. Oncotarget. 6(29):28401-24 (SCI).
  2. Chen SJ, Lin PW(林珮雯), Lin HP(林欣屏), Huang SS(黃聖翔), Lai FJ, Sheu HM, Hsu LJ, Chang NS. (2015) UV irradiation/cold shock-mediated apoptosis is switched to bubbling cell death at low temperatures. Oncotarget.
  3. Chang JY(張景雲), Lee MH, Lin SR, Yang LY, Sun HS, Sze CI, Hong Q, Lin YS, Chou YT, Hsu LJ, Jan MS, Gong CX, Chang NS. (2015) Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain. Oncotarget. 6(6):3578-89.
  4. Chang HT, Liu CC, Chen ST, Yap YV(葉綺雯), Chang NS*, Sze CI. (2015) Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductase. Exp Biol Med (Maywood). 240(3):329-37.
  5. Lee MH, Su WP(蘇婉佩), Wang WJ, Lin SR, Lu CY(盧貞伃), Chen YA(陳俞安), Chang JY(張景雲), Huang SS(黃聖翔), Chou PY(周沛宜), Ye SR, Chen SJ, He H, Liu TH, Chou YT, Hsu LJ, Lai FJ, Chen SJ, Lee HC, Kakhniashvili D, Goodman S, Chang NS. (2015) Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo.Oncotarget .6(6):3737-51.


  1. Tsung-Ming Chen(陳琮明)Yu-Heng Shih(石聿恆), Joseph T. Tseng, Chih-Hao Wu(吳志豪) ,Yi-Han Lee(李奕漢)Shaw-Jenq Tsai*, and H.Sunny Sun*. (2014) Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation. Nucleic acids research. 42(5):2932-44.
  2. Ya-Chi Lin(林雅琪), Joseph T. Tseng, Shuen-Lin Jeng and H. Sunny Sun*. (2014) Comprehensive analysis of common coding sequence variants in Taiwanese Han population. Biomarkers and Genomic Medicine. 6 :133-143
  3. Yi-Mei Joy Lin(林宜玫) ,Cheng-Da Hsu, Hsiao-Yen Hsieh, Chia-Chih Alex Tseng, H.Sunny Sun*. (2014) Sequence Variants of HTR3A Gene Contribute to Genetic Prediction of Postoperative Nausea in Taiwan. Journal of Human Genetics. 59:655-60
  4. Kuo YZ (郭怡孜)Tai YH (戴于涵), Lo HI, Chen YL, Cheng HC, Fang WY (方偉宇), Lin SH, Yang CL, Tsai ST, Wu LW. (2014 Apr) MiR-99a exerts anti-metastasis through inhibiting myotubularin-related protein 3 expression in oral cancer. Oral Diseases. 20:e65-75.
  5. Mo ST(莫舒婷) ,Chiang S J(江尚儒)Lai T Y(賴泰佑)Cheng Y L(鄭侑玲)Chung C E(鍾承恩), Kuo S C H, Reece K M, Chen Y C(陳永承)Chang N S, Wadzinski B E, and Chiang C. W. (2014). Visualization of subunit interactions and ternary complexes of protein phosphatase 2A in mammalian cells. PLoS One 9(12):e116074
  6. Li IC (李宜蓁)Chiu CY(邱建元)Wu CL(吳長霖)Chi JY(紀智瑛)Jian SR(簡孝儒)Wang SW, Chang CL. A dual-fluorescent reporter facilitates identification of thiol compounds that suppress microsatellite instability induced by oxidative stress. Free Radic Biol Med. 2014 Apr;69:86-95. SCI: Impact factor 5.736, Ranking 16/128.
  7. Y. W. Chen*, Ching-Hao Teng*, Y. H. Ho, T. Y. Ho, W. C. Huang (黃文俊), M. Hashimoto , I. Y. Chiang, and C. S. Chen. (2014) Identification of Bacterial Factors Involved in Type 1 Fimbria Expression using an Escherichia coli K12 Proteome Chip. Molecular and Cellular Proteomics. Molecular & cellular proteomics. (SCI). First Published on April 1, 2014, doi:10.1074/mcp.M113.035667 13(6):1485-94*Equal contribution to first authors.
  8. W. H. Lin, C. Y. Kao(高正彥)D. C. Yang, C. C. Tseng, A. B. Wu, Ching-Hao Teng, M. C. Wang J. J. Wu. (2014) Clinical and microbiologic characteristics of Klebsiella pneumoniae from community-acquired recurrent urinary tract infections. European journal of clinical microbiology & infectious diseases (SCI). 33:1533-9.
  9. Tsai CC(蔡政璋), Chen-Han, Yang CH(顏成翰)Chang NS . (2014) Role of Exosomes in Intercellular Signaling, Maintenance of Normal Physiology, and their Therapeutic Potentials (commentary).Clinical & Experimental Pharmacology. 4:154.


  1. Jia-Shing Chen(陳嘉興),Wei-Shiang Hung(洪偉翔)Hsiang-Han Chan(詹湘漢); Shaw-Jenq Tsai; H. Sunny Sun*. (2013) In silico identification of oncogenic potential of fyn-related kinase in hepatocellular carcinoma. Bioinformatics. 29(4): 420-7
  2. Su MT (蘇美慈), Lin SH, Chen YC, Wu LW, Kuo PL. (2013 Jun) Prokineticin receptor variants (PKR1-I379V and PKR2-V331M) are protective genotypes in human early pregnancy. Reproduction. 146(1):63-73 (SCI).
  3. Huang YH(黃議賢)Wu MP, Pan SC (潘信誠), Su WC, Chen YW, Wu LW . (2013) STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A-mediated angiogenic response partly via reduced bFGF production. Angiogenesis. 16(1):207-22.
  4. Wang JH, Cheng L(鄭烈), Wang CH, Ling W, Wang SW*, and Lee GB*. An integrated chip capable of performing sample pretreatment and nucleic acid amplification for HIV-1 detection. Biosensors and Bioelectronics, 2013 Mar, 41: 484-91. SCI: Impact factor 6.409, Ranking 1/28. Co-correspondence.
  5. Chiang MF, Chou PY(周沛宜), Wang WJ, Sze CI and Chang NS (2013) Tumor suppressor WWOX and p53 alterations and drug resistance in glioblastomas. Front Oncol. 3:43.
  6. Hong Q, Hsu LJ, Chou PY(周沛宜), Chou YT, Lu CY(盧貞伃), Chen YA(陳俞安)Chang NS (2013) Self-aggregating TIAF1 in lung cancer progression. Translational Respiratory Medicine. 1:5.


  1. Jia–Shing Chen(陳嘉興), Ih-Jen Su, Yu-Wei Leu, Kung-Chia Young, H. Sunny Sun*. (2012-Mar) Expression of T-Cell Lymphoma Invasion and Metastasis 2 Promotes Proliferation and Invasion in liver cancer. INTERNATIONAL JOURNAL OF CANCER. 130(6), 1302-13.
  2. Yu-Chen Jiang(姜俞臣)Hung-Ming Wu, Kai-Hsin Cheng and H. Sunny Sun*. (2012) Menstrual Cycle-dependent Febrile Episode Mediated by Sequence-specific Repression of Poly(ADP-ribose) Polymerase-1 on the Transcription of the Human Serotonin Receptor 1A Gene. Human Mutation. 33 (1) :209-17.
  3. Pan SC (潘信誠)Wu LW , Chen CL, Shieh SJ, and Chiu YC. (2012-Sep) Angiogenin expression in burn blister fluid: Implications for its role in burn wound neovascularization. Wound Repair and Regeneration. 20(5):731-9 (SCI).
  4. Tsai WC (蔡婉琪), Lin YC, Tsai ST, Shen WH (沈文豪)Chao TL (趙苔玲), Lee SL, and Wu LW. (2011) Lack of modulatory function of coding nucleotide polymorphism S100A2_185G>A in oral squamous cell carcinoma. Oral Diseases. 17:283-290.
  5. B. H. Mao (毛彬旭), Y. F. Chang, J. Scaria, C. C. Chang, L. W. Chou, N. Tien, J. J. Wu, C. C. Tseng, M. C. Wang, C. C. Chang, Y. M. Hsu, and Ching-Hao Teng*. (2012/2) Identification of Escherichia coli genes associated with urinary tract infections. Journal of clinical microbiology. 50:449-456. (SCI). *Corresponding Author.
  6. Y. T. Tseng (曾渝婷), S. W. Wang, K. S. Kim, Y. H. Wang, Y. Yao, C. C. Chen, C. W. Chiang, P. C. Hsieh, and Ching-Hao Teng*. (2012/10) NlpI facilitates deposition of C4bp on Escherichia coli by blocking classical complement-mediated killing, which results in high-level bacteremia. Infection and immunity. 80:3669-3678. (SCI). *Corresponding Author.
  7. C. Y. Wang (王琴雅), S. W. Wang, W. C. Huang (黃文俊), K. S. Kim, N. S. Chang, Y. H. Wang, M. H. Wu, and Ching-Hao Teng*. (2012/10) Prc contributes to Escherichia coli evasion of classical complement-mediated serum killing. Infection and immunity. 80: 3399-3409. (SCI). *Corresponding Author.
  8. Chang JY(張景雲), Chiang MF, Lin SR, Lee MH, He H, Chou PY(周沛宜), Chen SJ, Chen YA(陳俞安), Yang LY, Lai FJ, Hsieh TH, Sheu HM, Sze CI,Chang NS (2012) TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death. Cell Death &Disease. 3:e302.
  9. Chang JY(張景雲), Lee MH, Lin SR, Yang LY, Sze CI, Sheu HM, Lai FJ, Chang NS (2012) Self-aggregating mutant TRAPPC6A from partial exon 1 gene deletion activates caspases, binds TIAF1, and generates amyloid beta in hippocampus. The FASEB Journal. 752.2
  10. Chang JY(張景雲), Chiang MF, Lin SR, Lee MH, Chou PY(周沛宜), Yang LY, Sze CI, Sheu HM, Lai FJ, Chang NS (2012-Apr) TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53- deficient environment, and cell deat. Cell Death & Disease. 3:e302.doi: 10.1038/cddis.


  1. Ying-Fan Chen(陳盈帆)Chao-Ling Tung(董昭玲)Wen-Chi Hsiao(蕭汶琪)Yao Chang, lh-Jen Su and H. Sunny Sun*. (2011) Analysis of global methylation using a Zta¬expressing nasopharyngeal carcinoma cell line. Genomics. 97(4):205-13.
  2. Bing-Huang Gau, Tsung-Ming Chen(陳琮明)Yu-Herg J. Shih(石聿恆), and H. Sunny Sun*. (2011) FUBP3 interacts with FGF9 3' microsatellite and positively regulates FGF9 translation. Nucleic Acids Res. 39(9):3582-93.
  3. Tsai WC (蔡婉琪), Lin YC, Tsai ST, Shen WH (沈文豪)Chao TL (趙苔玲), Lee SL, and Wu LW. (2011) Lack of modulatory function of coding nucleotide polymorphism S100A2_185G>A in oral squamous cell carcinoma. Oral Diseases. 17:283-290.
  4. Lee JW (李峻瑋), Liao PC, Young KC, Chen SL, Chang CL, Cheng TS, Lai MD, Wang SW*. Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein. Journal of Proteome Research, 2011 Oct 7; 10(10):4522-34. Epub 2011 Aug.24. SCI: Impact factor 4.245, Ranking 14/79. Correspondence.
  5. Lin HP(林欣屏), Chang JY(張景雲), Huang SS(黃聖翔), Lin SR, Lee MH, Hsu LJ, Chang NS (2011, May) Identification of an in vivo MEK/WOX1 complex as a master switch for apoptosis in T cell leukemia. Genes & Cancer. 2(5): 550–562.doi:10.1177/1947601911418498
  6. Lin HP(林欣屏), Chang JY(張景雲), Huang SS(黃聖翔), Lin SR, Lee MH, Hsu LJ, Chang NS (2011) Phorbol ester dissociates an in vivo MEK/WOX1 complex for switching on a novel type of apoptosis in T lymphocytes. Genes & Cancer. 2:550-562.
  7. Chang NSChang JY(張景雲), Sze CI, Hong Q, Hsu LJ, Kuo YM, Chiang MF, Lee MH, Lin SR, Gong CX (2010) T TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease. Cell Death & Disease. 1(12):e110.
  8. Lee MH, Lin SR, Chang JY(張景雲), Schultz L, Heath J, Hsu LJ, Kuo YM, Hong Q, Chiang MF, Gong CX, Sze CI, Chang NS. (2010 Dec) TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease. Cell Death Dis. 23:1(12):e110.


  1. Tsung-Ming Chen(陳琮明)Chien-Hui Hsu(徐千惠), Shaw-Jenq Tsai, and H. Sunny Sun*. (2010) AUF1 p42 isoform selectively controls both steady-state and PGE2-induced FGF9 mRNA decay. Nucleic Acids Res. 38(22):8061-8071.
  2. Shin-Chih Chao(趙新志)Jia–Shing Chen(陳嘉興), Cheng-Hsien Tsai, Joy Yi-Mei Lin(林宜玫)Yuh-Jyh Lin, and H. Sunny Sun*. (2010) Novel exon nucleotide substitution at the splice junction causes a neonatal Marfan syndrome. Clinical Genetics. 77(5):453-463.
  3. Tsai ST, Chien IH (簡溢秀)Shen WH (沈文豪)Kuo YZ (郭怡孜), Jin YT, Wong TY, Hsiao JR, Wang HP, Shih NY, Wu LW. (2010) ENO1, a potentialprognostic head and neck cancer marker, promotes transformation partly via chemokine CCL20 induction. European Journal of Cancer. 46:1712-23.
  4. Pan SC (潘信誠)Wu LW (co-corresponder), Chen CL, Shieh SJ, Chiu HY. (2010) Deep partial thickness burn blister fluid promotes neovascularization in the early stage of burn wound healing. Wound Repair Regeneration. 18:311-8.
  5. He MF (何明芳)Huang YH(黃議賢)Wu LW (co-corresponder), Ge W, Shaw PC, and But PPH. (2010) Triptolide functions as a potent angiogenesis inhibitor. International Journal of Cancer. 126:266-278.
  6. Lee T. Y. (李定遠)Lai T. Y. (賴泰佑)Lin S. C(林信志)., Wu C. W., Ni I. F. (倪吟芬)Yang Y. S.(楊郁珊, Hung L. Y., Law B. K., and Chiang C. W. (2010, July) The B56γ3 Regulatory Subunit of Protein Phosphatase 2A(PP2A) Regulates S Phase-specific Nuclear Accumulation of PP2A and the G1 to S Transition. J. Biol. Chem. 285 (28): 21567-21580
  7. Chang JY(張景雲), He RY, Lin HP(林欣屏), Hsu LJ, Lai FJ, Hong Q, Chen SJ, Chang NS. (2010 Jul) Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase. Exp Biol Med (Maywood). 235(7):796-804.


  1. Lin, Yi-Mei J. (林宜玫)Huei-Chen Ko, Fong-Ming Chang, Tzung-Lieh Yeh, and H. Sunny Sun*. (2009) Population-specific functional variant of the TPH2 gene 2755C>A polymorphism contributes risk association to major depression and anxiety in Chinese peripartum women. Arch Womens Ment Health. 12(6):401–408.
  2. He MF (何明芳), Liu L, Ge W, Shaw PC, Jiang R, Wu LW, and But PPH. (2009) Antiangiogenic activity of Tripterygium wilfordii and its terpenoids. Journal of Ethnopharmacology. 121:61-8.
  3. Hong Q, Sze CI, Lin SR, Lee MH, He RY, Schultz L, Chang JY(張景雲), Chen SJ, Boackle RJ, Hsu LJ, Chang NS (2009) Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells. PLoS ONE. 4:e5755.
  4. Li MY, Lai FJ, Hsu LJ, Lo CP, Cheng CL, Lin SR, Lee MH, Chang JY(張景雲), Subhan D, Tsai MS, Sze CI, Pugazhenthi S, Chang NS*, Chen ST. (2009) Dramatic Co-Activation of WWOX/WOX1 with CREB and NF-kappaB in Delayed Loss of Small Dorsal Root Ganglion Neurons upon Sciatic Nerve Transection in Rats. PLoS One 4, e7820.


  1. Lin, Yi-Mei J. (林宜玫) ,Fabian Davamani, Wei-Chih Yang, Te-Jen Lai, and H.Sunny Sun*. 2008. Association analysis of monoamine oxidase A gene and bipolar affective disorder in Han Chinese. Behavioral and Brain Functions 4:21.
  2. Chen YH(陳雅惠), Huang YH(黃議賢), Wu HL, Wu MP (吳銘斌)Kuo YZ (郭怡孜), Chang WT, Lu KC and Wu LW. (2008) Angiostatin K1-3 induces E-selectin via AP1 and Ets1: a mediator for anti-angiogenic action of K1-3. Journal of Thrombosis and Haemostasis. 6: 1953-1961.
  3. Wu MP(吳銘斌), Young MJ, Tzeng CC, Tzeng CR, Huang KF, Wu LW (co-coresponder), Chou CY. (2008) A novel role of thrombospondin-1 in cervical carcinogenesis:Inhibit stroma reaction by inhibiting activated fibroblasts from invading cancer. Carcinogenesis. 29: 1115-23.
  4. Hu HT(胡曉棠)Huang YH (黃議賢), Chang YA, Lee CK, Jiang MJ, and Wu LW. (2008) Tie2-R849W mutant in venous malformations chronically activates a functional STAT1 to modulate gene expression. J. Invest. Dermatol. 128:2325-33.
  5. Kuo Y. C. (郭議駿)Huang K. Y. (黃凱芸)Yang C. H. (楊仲翔) ,Yang Y. S. (楊郁珊), Lee W. Y. and Chiang C. W. (2008) Regulation of Phosphorylation of Thr-308 of Akt, Cell Proliferation, and Survival by the B55α Regulatory Subunit Targeting of the Protein Phosphatase 2A Holoenzyme to Akt, J Biol. Chem. 283(4):1882-1892.


  1. Lin, Yi-Mei(林宜玫)Shin-Chih Chao(趙新志)Te-Jen Lai; Tsung-Ming Chen(陳琮明); Jia-Shing Chen(陳嘉興), and H. Sunny Sun* . 2007. Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in han chinese. Arch Gen Psychiatry 64:1015-1024.
  2. Chan, Hsiang-Han(詹湘漢), Shaw-Jenq Tsai, H. Sunny Sun*. 2007. TAG. Nucleic Acids Research Molecular Biology Database Collection #922.
  3. Chen, Tsung-Ming(陳琮明), Pao-Lin Kuo, Chien-Hui Hsu(徐千惠), Shaw-Jenq Tsai, Mong-Jen Chen, Chieh-Wei Lin and H. Sunny Sun*. 2007. Microsatellite in the 3’ untranslated region of human fibroblast growth factor 9 (FGF9) gene exhibits pleiotropic effect on modulating FGF9 protein expression. Human Mutation 28:98.
  4. Wu LW, Chiang YM, Chuang HC (莊曉菁), Lo CP, Yang KY, Wang SY, Shyur LF. (2007) A novel polyacetylene significantly inhibits angiogenesis and promotes apoptosis in human endothelial cells through activation of the CDK inhibitors and caspase-7. Planta Medica. 73:655-61.


  1. Chuang, Pei-Chin, H. Sunny SunTsung-Ming Chen(陳琮明), and Shaw-Jenq Tsai. 2006. Prostaglandin E-2 induces fibroblast growth factor 9 via EP3-dependent protein kinase C delta and Elk-1 signaling. MCB 26:8281-92.
  2. Ying-Fan Chen(陳盈帆), Po-Lin Kou, Shaw-Jenq Tsai, Ko-Fan Chen, Hsiang–Han Chan(詹湘漢)Chung Ming Chen(陳琮明), and H. Sunny Sun*. 2006. Computational analysis and refinement of sequence structure on chromosome 22q11.2 region: application to the development of quantitative real-time PCR assay for clinical diagnosis. Genomics 87290-297.
  3. Tsai WC(蔡婉琪), Tsai ST, Jin YT, and Wu LW. (2006) Cyclooxygenase 2 is involved in S100A2-mediated tumor suppression in squamous cell carcinoma. Mol Cancer Res. 4:539-547.
  4. Chen YH (陳雅惠), Wu HL, Li C, Huang YH (黃議賢), Chiang CW, Wu MP (吳銘斌)Wu LW. (2006) Anti-angiogenesis mediated by angiostatin K1-3, K1-4 and K1-4.5: Involvement of p53, FasL, AKT and mRNA deregulation. Thromb Haemost. 95:668-77.
  5. Tsai ST, Yang KY (楊凱英), Jin YT, Lin YC, Chang MT, and Wu LW. (2006) Amphiregulin as a Tumor Promoter for Oral Squamous Cell Carcinoma: Involvement of Cyclooxygenase 2. Oral Oncol. 42: 381-390.


  1. Tsai ST, Jin YT, Tsai WC(蔡婉琪), Wang ST, Lin YC (林宴君), Chang MT, and Wu LW. (2005) S100A2, a potential marker for early recurrence in early-stage oral cancer. Oral Oncol. 41:349-357.


  1. Lien WH (連文慧)Chen CK (陳啟寬)Lai LY, Chen YH(陳雅惠)Wu MP (吳銘斌), and Wu LW. (2004) Participation of cyclin D1 deregulation in TNP-470- mediated cytostatic effect: Involvement of senscence. Biochem. Pharmacol. 68:729-738.
  2. Tsai WC (蔡婉琪), Tsai ST, Ko JY, Jin YT, Li C, Huang W, Young KC, Lai MD, Liu HS, Wu LW. (2004) The mRNA profile of genes in betel-quid chewing oral cancer patients. Oral Oncol. 40:418-426.
  3. Wu MP (吳銘彬), Tzeng CC, Wu LW, Huang KF, Chou CY. (2004) The thrombospondin-1 acts as a fence to inhibit angiogenesis that occurs during cervical carcinogenesis. Cancer J. 10:27-32.


  1. Chen YH(陳雅惠), Wu HL, Chen CK, Huang YH, Yang BC, Wu LW. (2003) Angiostatin antagonizes the action of VEGF-A in human endothelial cells via distinct pathways. Biochem Biophys Res Comm. 310: 804-810.


  1. Chen YJ(陳怡如), Jin YT, Shieh DB, Tsai ST, and Wu LW. (2002) Molecular characterization of angiogenic properties in oral squamous cell carcinoma cells. Oral Oncology. 38:699–705.


  1. Jih YJ (紀盈志)Lien WH (連文慧), Tsai WC (蔡婉琪)Yang GW (楊介文), Li C, and Wu LW. (2001) Distinct regulation of genes by bFGF and VEGF in endothelial cells. Angiogenesis. 4: 313-21.
  2. Chen CC (陳金銓), Shieh B, Peck K, Tsai TS, Huang CH, Liau YE, Liou JT, Su IJ, Chow NH, Tzeng CC, Chiu WH, Jin YT, Wu LW, Huang W, Young KC, Lai MD, Liu HS, and Li C. (2001) Microarray profiling of gene expression patterns in bladder tumor cells treated with genistein. J. Biomed. Sci. 8:214-222.