2006 2007 2008   2009   2010   2011   2012   2013      
  2014 2015 2016   2017                  
    1. Su WP, Wang WJ, Sze CI,Chang NS (2016 Jul 28) Zfra induction of memory anticancer response via a novel immune cell. Oncoimmunology 5(9) e1213935 17/213(7.9%)
    2. Hsu LJ, Hong Q, Chen ST, Kuo HL, Schultz L, Heath J, Lin SR, Lee MH, Li DZ, Li ZL, Cheng HC, Armand G, Chang NS (2016 Nov 10) Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed. Oncotarget. doi: 10.18632/oncotarget. 36/213(16.9%)
    3. Hsu LJ, Chiang MF, Sze CI, Su WP, Yap YV, Lee IT, Kuo HL,Chang NS (2016 Dec 6) HYAL-2-WWOX-SMAD4 Signaling in Cell Death and Anticancer Response. Front Cell Dev Biol.4(141) doi: 10.3389/fcell.2016.00141
    4. Huang SS, Chang NS Specific phosphorylation of tumor suppressor WWOX drives terminal maturation of acute lymphoblastic leukemia MOLT-4 cell. J. Biol. Chem. , Impact factor 4.258, Ranking 71/289 (24.56%)
    5. Chang NS (2016 Jun.) Bubbling cell death: a hot air balloon released from the nucleus in the cold. Exp Biol Med (Maywood)241(12):1306-15, Impact factor 2.542, Ranking 57/124 (45.96%)
    6. Huang SS, Chang NS Specific phosphorylation of tumor suppressor WWOX drives terminal maturation of acute lymphoblastic leukemia MOLT-4 cell. J. Biol. Chem. , Impact factor 4.258, Ranking 71/289 (24.56%)
    7. Chou PY, Chen YA, Su WP, Lee MH, Lin SR, Chang JY, Lu CY, Doherty J, Kovach A, Chou YT, Hsu LJ, Lin YS, Chang NS WWOX confers repellence via C-terminal SDRrepl or attraction via N-terminal WWgre in cell-to-cell recognition. J. Biol. Chem., Impact factor 4.258, Ranking 71/289 (24.56%)
    8. Huang SS, Su WP, Lin HP, Kuo HL, Wei HL, Chang NS. (2016 Jun. 23) Role of WW domain-containing oxidoreductase WWOX in driving T-cell acute lymphoblastic leukemia maturation. J Biol Chem. pii: jbc.M116.716167, Impact factor 4.258, Ranking 71/289 (24.56%)
    9. Hung IC, Hsiao YC, Sun HS,Chen TM, Lee SJ. (2016 Nov. 15)MicroRNAs regulate gene plasticity during cold shock in zebrafish larvae. BMC Genomics. 17(1) 922 32/161 (19.9%)
    10. Wei-Hsuan Yen, Wu-Sian Ke, Jan-Jong Hung, Tsung-Ming Chen, Jia-Shing Chen, H. Sunny Sun* (2016 Jan. 14) Sp1-mediated ectopic expression of T-cell lymphoma invasion and metastasis 2 in hepatocellular carcinoma Cancer Medicine. 5(3):465-77, Impact factor 2.915, Ranking 107/213 (50.2%)
    11. Huang SM, Liao WT, Lin CF, Sun HS, Chow NH (2016 Mar.) Effectiveness and Mechanism of Preoperative Lugol Solution for Reducing Thyroid Blood Flow in Patients with Euthyroid Graves' Disease World J Surg.40(3):505-9, Impact factor 2.523, Ranking 52/199 (26.1%)
    12. Lai MC, Sun HS, Wang SW, Tarn WY (2015 Oct. 31) DDX3 functions in antiviral innate immunity through translational control of PACT "FEBS J. ISSN: 1742-464X"283(1):88-101, Impact factor 4.237, Ranking 72/289 (24.9%)
    13. Lai MS, Wang CY, Yang SH, Wu CC, Sun HS, Tsai SJ, Chuang JI, Chen YC, Huang BM. (2016 Apr. 2) The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes. Organogenesis12(2):61-77, Impact factor 2.91, Ranking 15/76 (19.7%)
    14. Lai MC, Chang CM, Sun HS. (2016 Apr. 14) Hypoxia Induces Autophagy through Translational Up-Regulation of Lysosomal Proteins in Human Colon Cancer Cells. PLoS One.11(4):e0153627, Impact factor 3.057, Ranking 11/63 (17.5%)
    15. Lai WC, Sun HS, Lin PH, Lin H, Shieh JC (2016 Feb.) A new rapid and efficient system with dominant selection developed to inactivate and conditionally express genes in Candida albicans. Current Genetics62(1):213-35, Impact factor 3.385, Ranking 54/165 (32.7%)
    16. Chun-Wei Chien, Pei-Chi Hou, Han-Chung Wu, Yu-Ling Chang, Shih-Chieh Lin, Shau-Chieh Lin, Bo-Wen Lin, Jenq-Chang Lee, Yu-Jia Chang, and H. Sunny Sun* (2016 May. 2) Targeting TYRO3 inhibits epithelial-mesenchymal transition and increases drug sensitivity in colon cancer Oncogene [Epub ahead of print], Impact factor 7.932, Ranking 15/213 (7.0%)
    17. Lai TY, Yen CJ, Tsai HW, Yang YS, Hong WF, Chiang CW (2016 Jan. 26) The B56γ3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1 Oncotarget.7(4):4542-58, Impact factor 6.356, Ranking 9.95%(21/211 in Oncology)
    18. Cheng CW, Hsiao JR, Fan CC, Lo YK, Tzen CY, Wu LW, Fang WY, Cheng AJ, Chen CH, Chang IS, Jiang SS, Chang JY, Lee AY. (2016 May.) Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma. Mol Carcinog. 55(5):499-513, Impact factor 4.722, Ranking 41/213 (19.71%)
    19. Lee NY, Wang JC, Lin YC, Wu CJ, Li CW, Li MC, Wang SW, Tseng FC, Ko WC (2016 Jun.) Characterization of the Near Full-Length Genome of a Novel HIV-1 CRF01_AE/CRF07_BC Recombinant in an Injection Drug User from Southern Taiwan AIDS Res Hum Retroviruses32(6):588-94, Impact factor 1.949, Ranking 56/83 (68%)
    20. Lai MC, Sun HS, Wang SW, Tarn WY (2016 Jan.) DDX3 functions in antiviral innate immunity through translational control of PACT FEBS J.283(1):88-101, Impact factor 4.001, Ranking 77/290 (26.6%)
    21. Takahashi H, Koda M, Hashimoto M, Furuya T, Sakuma T, Kato K, Okawa A, Inada T, Kamiya K, Ota M, Maki S, Takahashi K, Yamazaki M, Mannoji C. (2016) Transplanted Peripheral Blood Stem Cells Mobilized by Granulocyte Colony-Stimulating Factor Promoted Hindlimb Functional Recovery After Spinal Cord Injury in Mice. Cell Transplant. 25(2):283-92
    22. Wang S, Chu CH, Guo M, Jiang L, Nie H, Zhang W, Wilson B, Yang L, Stewart T, Hong JS, Zhang J. (2016 Jun. 21) Identification of a specific α-synuclein peptide (α-Syn 29-40) capable of eliciting microglial superoxide production to damage dopaminergic neurons. J Neuroinflammation.13(1):158, Impact factor 5.408, Ranking 11/83 (13.2%)
    23. Chang TT, Chen SL, Chang YH, Chen PS, Chu CH, Chen SH, Huang SY, Tzeng NS, Wang LJ, Wang TY, Li CL, Chung YL, Hsieh TH, Lee IH, Chen KC, Yang YK, Hong JS, Lu RB, Lee SY. (2016 Jun.) The DRD3 Ser9Gly Polymorphism Predicted Metabolic Change in Drug-Naive Patients With Bipolar II Disorder. Medicine (Baltimore)95(24):e3488, Impact factor 5.723, Ranking 359/1779 (20.1%)
    24. Wang TY, Lee SY, Chen SL, Chang YH, Wang LJ, Chen PS, Chen SH, Chu CH, Huang SY, Tzeng NS, Li CL, Chung YL, Hsieh TH, Lee IH, Chen KC, Yang YK, Hong JS, Lu RB. (2016 Jun. 7) Comparing clinical responses and the biomarkers of BDNF and cytokines between subthreshold bipolar disorder and bipolar II disorder. Sci Rep.6:27431, Impact factor 5.578, Ranking 4/111 (3.6%)
    25. Chu CH, Wang S, Li CL, Chen SH, Hu CF, Chung YL, Chen SL, Wang Q, Lu RB, Gao HM, Hong JS. (2016 Jul.) Neurons and astroglia govern microglial endotoxin tolerance through macrophage colony-stimulating factor receptor-mediated ERK1/2 signals. Brain Behav Immun. 55:260-72., Impact factor 5.889, Ranking 2/60 (3.3%)
    26. Wang TY, Lee SY, Chung YL, Chen SL, Li CL, Chang YH, Wang LJ, Chen PS, Chen SH, Chu CH, Huang SY, Tzeng NS, Hsieh TH, Lee IH, Chen KC, Yang YK, Hong JS, Lu RB. (2016) TPH1 and 5-HTTLPR Genes Specifically Interact in Opiate Dependence but Not in Alcohol Dependence. Eur Addict Res.22(4):201-9, Impact factor 2.101, Ranking 23/229 (10%)
    27. Wang TY, Lee SY, Chen SL, Chung YL, Li CL, Chang YH, Wang LJ, Chen PS, Chen SH, Chu CH, Huang SY, Tzeng NS, Hsieh TH, Chiu YC, Lee IH, Chen KC, Yang YK, Hong JS, Lu RB. (2016 Apr 15) The Differential Levels of Inflammatory Cytokines and BDNF among Bipolar Spectrum Disorders. Int J Neuropsychopharmacol. pii: pyw012. doi: 10.1093/ijnp/pyw012., Impact factor 4.009, Ranking 38/329 (11.5%)
    1. SChang NS. (2015). Introduction to a thematic issue for WWOX. Professor Exp Biol Med (Maywood). 240(3):281-4
    2. In Memoriam: Shur-Tzu (Su) Chen, a pioneer in tumor suppressor WWOX for neuroscience. Professor Nan-Shan Chang
    3. A Thematic Issue for Tumor Suppressor WWOX in Cancer, Metabolism and Neural Diseases has been published in Experimental Biology and Medicine in March [240 (3), 2015]. Professor Nan-Shan Chang is the Editor-in-Chief.>
    4. Chang NS. (2015) Introduction to a Thematic Issue for WWOX. Exp Biol Med (Maywood). 240(3):281-4:doi: 10.1177/1535370215574226.
    5. Da Sie Y, Li YC, Chang NS, Campagnola PJ, Chen SJ. (2015) Fabrication of three-dimensional multi-protein microstructures for cell migration and adhesion enhancement. Biomed Opt Express. 240(3):281-4:doi: 10.1177/1535370215574226.
    6. Chen SJ, Lin PW, Lin HP, Huang SS, Lai FJ, Sheu HM, Hsu LJ, Chang NS. (2015) UV irradiation/cold shock-mediated apoptosis is switched to bubbling cell death at low temperatures. Oncotarget.
    7. Chang JY, Lee MH, Lin SR, Yang LY, Sun HS, Sze CI, Hong Q, Lin YS, Chou YT, Hsu LJ, Jan MS, Gong CX, Chang NS. (2015) Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain. Oncotarget. 6(6):3578-89.
    8. Chang HT, Liu CC, Chen ST, Yap YV, Chang NS*, Sze CI. (2015) Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductase. Exp Biol Med (Maywood). 240(3):329-37.
    9. Lee MH, Su WP, Wang WJ, Lin SR, Lu CY, Chen YA, Chang JY, Huang SS, Chou PY, Ye SR, Chen SJ, He H, Liu TH, Chou YT, Hsu LJ, Lai FJ, Chen SJ, Lee HC, Kakhniashvili D, Goodman S, Chang NS. (2015) Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo.Oncotarget .6(6):3737-51.
    10. Wang HC, Cheng FC, Wu MS, Shu HY, Sun HS, Wang YC, Su IJ, Wu CJ. (2015) Genome Sequences of Three Helicobacter pylori Strains from Patients with Gastric Mucosa-Associated Lymphoid Tissue Lymphoma. Genome Announc. 3(2):pii:e00229-15. doi: 10.1128/genomeA.00229-15.
    11. Chang JY, Lee MH, Lin SR, Yang LY, Sun HS, Sze CI, Hong Q, Lin YS, Chou YT, Hsu LJ, Jan MS, Gong CX, Chang NS. (2015) Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain. Oncotarget. 6(6):3578-89.
    12. Liang KC, Tseng JT, Tsai SJ, Sun HS. (2015) Characterization and distribution of repetitive elements in association with genes in the human genome. Comput Biol Chem. pii: S1476-9271(15)00024-9.
    13. Wei-Yu Fang, Yi-Wen Chen, Jenn-Ren Hsiao, Chiang-Shin Liu, Yi-Zih Kuo, Yi-Ching Wang, Kung-Chao Chang, Sen-Tien Tsai, Mei-Zhu Chang, Siao-Han Lin, and Wu LW. (Accepted). Elevated S100A9 expression in tumor stroma functions as an early recurrence marker for early-stage oral cancer patients through increased tumor cell invasion, angiogenesis, macrophage recruitment and interleukin-6 production. Oncotarget. (SCI).
    14. Tang YA, Chen CH, Sun HS, Cheng CP, Tseng VS, Hsu HS, Su WC, Lai WW, Wang YC. (2015) Global Oct4 target gene analysis reveals novel downstream PTEN and TNC genes required for drug-resistance and metastasis in lung cancer. Nucleic Acids Res.43(3):1593-60.
    15. Taniguchi1 K, Wu LW, Grivennikov SI, Jong PR, Lian I, Yu FX, Wang K, Ho SB, Boland BS,Chang JT, Sandborn WJ, Hardiman G, Raz E, Maehara Y, Yoshimura A, Jessica Zucman-Rossi J, Guan KL, Karin M. (2015 Mar). A gp130-Src-YAP module links intestinal injury and inflammation to epithelial regeneration. Nature 519:57-62 (SCI).
    16. Cheng CW, Hsiao JR, Fan CC, Lo YK, Tzen CY, Wu LW, Fang WY, Cheng AJ, Chen CH, Chang IS, Jiang SS, Chang JY, and Lee AY. (2015 Mar) Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma. Mol Carcinogen doi: 10.1002/mc.22297.
    17. Wu JM, Hsueh YC, Ch’ang HU, Luo CY, Wu LW, Nakauchi H, Hsieh PC. (2015 Feb)  Circulating cells contribute to cardiomyocyte regeneration after injury. Circ Res. 116(4):633-41 (SCI).
    18. Yang CP, Chiang C. W., Chen CH, Lee YC, Wu MH, Tsou YH, Yang YS, Chang WC, Lin DY. (2015). Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58). J Biomed Sci.2233-47 Visualization of subunit interactions and ternary complexes of protein phosphatase 2A in mammalian cells.  PLoS One 9(12):e116074
    19. Kurata, T., Nakanishi, S., Hashimoto, M., Taoka, M., Yamazaki, Y., Isobe, T., and Kato, J. (2015) Novel essential gene involved in 16S rRNA processing in Escherichia coli. Journal of Molecular Biology. 427 (4) 955-965.
  1. Ya-Chi Lin, Joseph T. Tseng, Shuen-Lin Jeng and H. Sunny Sun. Comprehensive analysis of common coding sequence variants in Taiwanese Han population.Biomarkers and Genomic Medicine(2014)

  2. Chang JY, Lee MH, Lin SR, Yang LY, Sun HS, Sze CI, Hong Q, Lin YS, Chou YT, Hsu LJ, Jan MS, Gong CX, Chang NS.Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain.

  3. Chang HT, Liu CC, Chen ST, Yap YV, Chang NS*, Sze CI*.WW domain-containing oxidoreductase in neuronal injury and neurological diseases. Oncotarget .

  4. Lee MH, Su WP, Wang WJ, Lin SR, Lu CY, Chen YA, Chang JY, Huang SS, Chou PY, Ye SR, Chen SJ, He H, Liu TH, Chou YT, Hsu LJ, Lai FJ, Chen SJ, Lee HC, Kakhniashvili D, Goodman S, Chang NS, Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo. Oncotarget

  5. Mo S. T., Chiang S. J., Lai T. Y., Cheng Y. L., Chung C. E., Kuo S. C., Reece K. M., Chen Y. C., Chang N. S., Wadzinski B. E., and Chiang C. W. (corresponding)Visualization of subunit interactions and ternary complexes of protein phosphatase 2A in mammalian cells. (2014)PLoS One.

  6. Wu JM, Hsueh YC, Ch’ang HU, Luo CY, Wu LW, Nakauchi H, Hsieh PC. Circulating cells contribute to cardiomyocyte regeneration after injury.  Circ Res [SCI, Epub ahead of print].

  7. Wang K, Kim M., Caro1 GD, Wong J, Shalapour S, Wan J, Zhang W, Zhong Z,Wu LW, Taniguchi K., Feng Y, Fearon E, Grivennikov SI, and Karin M. Inteleukin-17 A receptor A signals in transformed enterocytes to promote early colorectal tumorigenesis. Immunity (SCI, accepted).

  8. Wu X, Zhang W, Font-Burgada J, Palmer T, Hamil AS, Biswas SK, Poidinger M, Borcherding N, Xie Q, Ellies LG, Lytle NK, Wu LW , Fox RG, Yang J, Dowdy SF, Reya T, Karin M.(2014) Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.Proc Natl Acad Sci U S A. pii: 201414358.  

  9. Tsai CC, Chen-Han Yang CH, Chang NS . (2014) Role of Exosomes in Intercellular Signaling, Maintenance of Normal Physiology, and their Therapeutic Potentials (commentary).Clinical & Experimental Pharmacology. 4:154.

  10. Yu-Tzu Chang, Ming-Cheng Wang, An-Bang Wu, Junne-Ming Sung,H. Sunny Sun, Ih-Jen Su, Wei-ChihKan, Chih- Chiang Chien, Jyh-Chang Hwang, Hsien-Yi Wang, Chin-Chung Tseng, and Chi-Jung Wu. (2014) Rapid Identification of Bacteria and Candida Pathogens in Peritoneal Dialysis Effluent from Patients with Peritoneal Dialysis-Related Peritonitis Using Multilocus PCR Coupled with Electrospray Ionization Mass Spectrometry. J ClinMicrobiol. 52(4):1217-1219.

  11. Kuo PH, Chuang LC, Liu JR, Liu CM, Huang MC, Lin SK, Sun HS, Hsieh MH, Hung H, Lu RB. (2014) Identification of novel loci for bipolar I disorder in a multi-stage genome-wide association study. Neuro-Psychopharmacology &Biological Psychiatry. 51:58-64.

  12. Chen TM, Shih YH, Tseng JT, Lai MC, Wu CH, Li YH, Tsai SJ,Sun HS. (2014). Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation. Nucleic Acids Res. 42(5): 2932-44.

  13. Wen-Chi Jan, Shi-Yi Yang, Li-Chung Chuang, Ru-Band Lu, Ming-Kun Lu, H. S. Sun,Po-HsiuKuo. (2014) Exploring the associations between genetic variants in genes encoding for subunits of calcium channel and subtypes of bipolar disorder. J Affect Disord. 20(157) :80-86.

  14.  Chi-Jung Wu, M.D.; Ya-Pin Chen; Hsuan-Chen Wang;Ih-Jen Su; Wen-ChienKo; Jiann-Shiuh Chen; Chao-NengCheng;Nan-Yao Lee; H. Sunny Sun; Chia-Yu Chi; Tsai-Yun Chen. (2014) Identification of Fungal Pathogens from Clinical Specimens using Multi-locus PCR Coupled with Electrospray Ionization Mass Spectrometry. Diagnostic Microbiology and Infectious Disease DiagnMicrobiol Infect. 78(2):141-143.

  15. Wan-Lin Liao, Shao-Chieh Lin, H. Sunny Sun*, Shaw-Jenq Tsai*. (2014) Hypoxia-induced tumor malignancy and drug resistance: Role of microRNAs. Biomarkers and Genomic Medicine. 6(1)1-11.

  16. Tsung-Ming Chen, Yu-Heng Shih, Joseph T. Tseng, Chih-Hao Wu, Yi-Han Lee, Shaw-Jenq Tsai*, andH. Sunny Sun*. (2014) Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation. Nucleic acids research.42(5):2932-44.

  17. Kuo YZ, Tai YH, Lo HI, Chen YL, Cheng HC, Fang WY, Lin SH, Yang CL, Tsai ST, Wu LW. (2014.4) MiR-99a exerts anti-metastasis through inhibiting myotubularin-related protein 3 expression in oral cancer. Oral Diseases. 20:e65-75.

  18. Y. W. Chen*, Ching-HaoTeng*, Y. H. Ho, T. Y. Ho, W. C. Huang, M. Hashimoto, I. Y. Chiang, and C. S. Chen. (2014) Identification of Bacterial Factors Involved in Type 1 Fimbria Expression using an Escherichia coli K12 Proteome Chip. Molecular and Cellular Proteomics. Molecular & cellular proteomics. (SCI) .13(6):1485-94. contribution to first authors.

  19. W. H. Lin, C. Y. Kao, D. C. Yang, C. C. Tseng, A. B. Wu, Ching-HaoTeng, M. C. Wang,J. J. Wu. (2014) Clinical and microbiologic characteristics of Klebsiellapneumoniae from community-acquired recurrent urinary tract infections. European journal of clinical microbiology & infectious diseases (SCI). 33:1533-9. 

  20. Li IC, Chiu CY, Wu CL, Chi JY, Jian SR, Wang SW ,Chang CL. (2014) A dual-fluorescent reporter facilitates identification of thiol compounds that suppress microsatellite instability induced by oxidative stress. Free RadicBiol Med. 69:86-95.

  21. Manrique M, Kozlowski PA, Cobo-Molinos A, Wang SW, Wilson RL, Martinez-ViedmaMdel P, Montefiori DC, Carville A, Aldovini A. (2014) Resistance to infection, early and persistent suppression of simian immunodeficiency virus SIVmac251 viremia, and significant reduction of tissue viral burden after mucosal vaccination in female rhesus macaques. J Virol. 88(1):212-24

  22. Lee JC, Tseng CK, Young KC, Sun HY, Wang SW, Chen WC, Lin CK, Wu YH. (2014) Andrographolide exerts anti-hepatitis C virus activity by up-regulating haeme oxygenase-1 via the p38 MAPK/Nrf2 pathway in human hepatoma cells. 171(1):237-52.




1.          Chiang MF, Chen ST, Lo CP, Sze CI, Chang NS. Chen YJ. (2013) Expression of WW domain-containing oxidoreductase WOX1 in human nervous system tumors. Anal Cell Pathol (Amst). 36(5-6):133-47.

2.          Chung CL, Lu CW, Cheng YS, Lin CY, Sun HS*, Lin YM*. (2013) Association of aberrant expression of sex-determining gene fibroblast growth factor 9 with Sertoli cell-only syndrome. Fertility and Sterility. 100(6):1547-1554.

3.          Su MT, Liang YL, Chen JC, Sun HS, Chang FM, Kuo PL. (2013) Non-mosaic uniparental trisomy 16 presenting with asplenia syndrome and placental abruption: a case report and literature review. European journal of medical genetics. 56(4):197-201.

4.          Chi-Jung Wu, Hsuan-Chen Wang, Po-Lin Chen, Ming-Chung Chang, H. Sunny Sun, Pei-Hsin Chou, Wen-Chien. (2013) AQU-1, a chromosomal class C b-lactamase, among clinical Aeromonasdhakensis isolates: Distribution and clinical significance. International Journal of Antimicrobial Agents. Int J Antimicrob Agents. 42(5):456-461.

5.          Ming-Chih Lai, Shainn-Wei Wang, Lie Cheng,Woan-Yuh Tarn, Shaw-Jenq Tsai* and H. Sunny Sun*. (2013) Human DDX3 Interacts with the HIV-1 Tat Protein to Facilitate Viral mRNA Translation.PLoS ONE. 8(7):e68665.

6.          Chiu HC, Chow KC, Fan YH, Chang SC, Chiou SH*, Chiang SF, Chiou CH, Wu GH, Yang HC, Ho SP, Chen YK, Lee WC, Sun HS. (2013) Expression of EBV-encoded oncogenes and EBV-like virions in multiple canine tumors. Veterinary microbiology. 163(1-2) :79-89

7.          Jia-Shing Chen; Wei-Shiang Hung; Hsiang-Han Chan; Shaw-Jenq Tsai; H. Sunny Sun*. (2013) In silico identification of oncogenic potential of fyn-related kinase in hepatocellular carcinoma. Bioinformatics. 29(4): 420-7.

8.          H.P. Su, C.J. Hou, W.H. Chen, K.J. Wang, Y.H. Chiu, H.S. Sun.* (2013) A miniature lighted stylet for fast oral endotracheal intubation in rabbits. The Veterinary Journal. 195(2): 254-6.

9.          Chiang MF, Chen ST, Lo CP, Sze CI, Chang NS , Chen YJ. (2013) Expression of WW domain-containing oxidoreductase WOX1 in human nervous system tumors. Anal Cell Pathol (Amst). 36:133-47.

10.      Chiang MF, Chou PY, Wang WJ, Sze CI and Chang NS (2013) Tumor suppressor WWOX and p53 alterations and drug resistance in glioblastomas. Front Oncol. 3:43.

11.      Sze C, Su W, Chiang M, Chen Y and Chang NS (2013) Assessing current therapeutic approaches to decode potential resistance mechanisms in glioblastomas. Front Oncol. 3:59.

12.      Hong Q, Hsu LJ, Chou PY, Chou YT, Lu CY, Chen YA, Nan-Shan Chang NS (2013) Self-aggregating TIAF1 in lung cancer progression. Translational Respiratory Medicine. 1:5.

13.      Su MT, Lin SH, Chen YC, Wu LW, Kuo PL. (2013 Jun) Prokineticin receptor variants (PKR1-I379V and PKR2-V331M) are protective genotypes in human early pregnancy. Reproduction. 14;146(1):63-73. doi: 10.1530/REP-13-0043.

14.      Huang YH, Wu MP, Pan SC, Su WC, Chen YW, Wu LW . (2013) STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A-mediated angiogenic response partly via reduced bFGF production. Angiogenesis. 16(1):207-22.

15.      M. C. Wang, W. H. Lin, C. C. Tseng, A. B. Wu, Ching-HaoTeng, J. J. Yan, J. J. Wu. (2013/3) Role of K1 capsule antigen in cirrhotic patients with Escherichia coli spontaneous bacterial peritonitis in southern Taiwan. European journal of clinical microbiology & infectious diseases. 32:407-412. (SCI).

16.      M. C. Wang, C. C. Tseng, An. B. Wu, W. H. Lin, Ching-HaoTeng, J. J. Yan,J. J. Wu.(2013/2) Bacterial characteristics and glycemic control in diabetic patients with Escherichia coli urinary tract infection. Journal of microbiology, immunology and infection. 46:24-29. (SCI).

17.      Manrique M, Koziowski PA, Cobo-Molinos A, Wang SW, Wilson RL, Montefiori DC, Carvile A, Aldovini A. (2013 Feb) Immunogenicity of a vaccine regimen composed of simian immunodeficiency virus DNA, rMVA, and viral particles administered to female rhesus macaques via four different mucosal routes. J. Virol. 13. 87:4738-50.

18.      Wang JH, Cheng L, Wang CH, Ling W, Wang SW*, and Lee GB*. (2013 Mar) An integrated chip capable of performing sample pretreatment and nucleic acid amplification for HIV-1 detection. Biosensors & Bioelectronics. 15, 41:484-91.

19. Sun HY, Lin CC, Lee JC, Wang SW, Cheng PN, Wu IC, Chang TT, Lai MD, Shieh DB, Young KC. (2013) Very low-density lipoprotein/lipo-viro particles reverse lipoprotein lipase-mediated inhibition of hepatitis C virus infection via apolipoprotein C-III. Gut. 62:1193-203.



1.      Lin MW, Tsai SJ, Chou PY, Huang MF, Sun HS, Wu MH. (2012) Vitamin D receptor 1a promotor -1521 G/C and -1012 A/G polymorphisms in polycystic ovary syndrome. Taiwan J Obstet Gynecol. 51(4):565-71

2.      Jia–Shing Chen, Ih-Jen Su, Yu-Wei Leu, Kung-Chia Young, H. Sunny Sun*. (2012-Mar) Expression of T-Cell Lymphoma Invasion and Metastasis 2 Promotes Proliferation and Invasion in liver cancer. INTERNATIONAL JOURNAL OF CANCER. 130(6), 1302-13.

3.      Yu-Chen Jiang, Hung-Ming Wu, Kai-Hsin Cheng and H. Sunny Sun*. (2012) Menstrual Cycle-dependent Febrile Episode Mediated by Sequence-specific Repression of Poly(ADP-ribose) Polymerase-1 on the Transcription of the Human Serotonin Receptor 1A Gene. Human Mutation. 33 (1) :209-17.

4.      Chang JY, Chiang MF, Lin SR, Lee MH, He H, Chou PY, Chen SJ, Chen YA, Yang LY, Lai FJ, Hsieh TH, Sheu HM, Sze CI,Chang NS (2012) TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death. Cell Death &Disease. 3:e302.

5.      Chiang MF, Yeh ST, Liao HF, Chang N-S, Chen YJ (2012) Overexpression of WW domain-containing oxidoreductase WOX1 preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. Biomedicine & Pharmacotherapy. doi:10.1016/j.biopha.2012.03.003

6.      Lee MH, Lin SR, Chang N-S (2012) Covalent modification of proteins by a small peptide Zfra. The FASEB Journal. 838.2.

7.      Chang JY, Lee MH, Lin SR, Yang LY, Sze CI, Sheu HM, Lai FJ, Chang N-S (2012) Self-aggregating mutant TRAPPC6A from partial exon 1 gene deletion activates caspases, binds TIAF1, and generates amyloid beta in hippocampus. The FASEB Journal. 752.2

8.      Wang CY, Wang SW, Huang WC, Kim KS, Chang NS, Wang YH, Wu MH, Teng CH. (2012 Jul 23) Prc contributes to Escherichia coli evasion of classical complement-mediated serum killing. Infect Immun. 80:3399-409.

9.      Lin CY, Lien CH, Cho KC, Chang CY, Chang NS, Campagnola PJ, Dong CY, Chen SJ. (2012 Jun) Investigation of two-photon excited fluorescence increment via crosslinked bovine serum albumin. Opt Express. 18;20(13):13669-13676. doi: 10.1364/OE.20.013669.

10.  Wang HY, Juo LI, Lin YT, Hsiao M, Lin JT, Tsai CH, Tzeng YH, Chung YC, Chang NS, Yang CN, Lu PJ (2012-Jun) WW domain-containing oxidoreductase promotes neuronal differentiation via negative regulation of glycogen synthase kinase 3β. Cell Death differ. 19(6), 1049-1059.doi: 10.1038/cdd.2011.188.

11.  Chang JY, Chiang MF, Lin SR, Lee MH, Chou PY, Yang LY, Sze CI, Sheu HM, Lai FJ, Chang NS (2012-Apr) TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53- deficient environment, and cell deat. Cell Death & Disease. 3:e302.doi: 10.1038/cddis.

12.  Cheng LC, Chang CY, Lin CY, Cho KC, Yen WC, Chang NS, Xu C, Dong CY, Chen SJ (2012-Apr) Spatiotemporal focusing- based widefieldmultiphoton microscopy for fast optical sectioning. Opt Express. 9:20(8):8939-48. doi: 10.1364/OE.20.008939..

13.  Maity JP, Nath B, Kar S, Chen C-Y, Banerjee S, Jean J-S, Liu M-Y, Centeno JA, Bhattacharya P, Chang CL and Santra SC. (2012) Arsenic-induced health crisis in peri-urban Moyna and Ardebok villages, West Bengal, India: an exposure assessment study. Environ Geochem Health 34: 563-74.

14.  Y. T. Tseng,S. W. Wang, K. S. Kim, Y. H. Wang, Y. Yao, C. C. Chen, C. W. Chiang, P. C. Hsieh, and Ching-HaoTeng*. (2012) NlpI Facilitates deposition of C4bp on Escherichia coli by blocking classical complement-mediated killing, which results in high-level bacteremia. Infection and immunity. 80:3669-78. (SCI). *Corresponding Author.

15.  Yen C. J., Lin Y. J., Yen C. S., Tsai H. W., Tsai T. F., Chang K. Y., Huang W. C., Lin P. W., Chiang C. W., Chang T. T. (co-corresponding). (2012) Hepatitis B Virus X Protein UpregulatesmTOR Signaling through IKKβ to Increase Cell Proliferation and VEGF Production in Hepatocellular Carcinoma. PLoS One. 7(7):e41931.

16.  Pan SC, Wu LW , Chen CL, Shieh SJ, and Chiu YC. (2012-Sep) Angiogenin expression in burn blister fluid: Implications for its role in burn wound neovascularization. Wound Repair and Regeneration. 20(5):731-9 (SCI).

17.  T. Janvilisri, J. Scaria, Ching-HaoTeng, S. P. McDonough, R. D. Gleed, S. L Fubini, S. Zhang, B. L. Akey, Y. F. Chang. (2012/9) Temporal differential proteomes of Clostridium difficile in the pig ileal-ligated loop model.PLoS One. 7:e45608. (SCI).

18.  Y. F. Liu, J. J. Yan, H. Y. Lei, Ching-HaoTeng, M. C. Wang, C. C. Tseng, and J. J. Wu. (2012/5) Loss of outer membrane protein C in Escherichia coli contributes to both antibiotic resistance and escaping antibody-dependent bactericidal activity. Infection and immunity. 80: 1815-1822. (SCI).

19. B. H. Mao, Y. F. Chang, J. Scaria, C. C. Chang, L. W. Chou, N. Tien, J. J. Wu, C. C. Tseng, M. C. Wang, C. C. Chang, Y. M. Hsu, and Ching-HaoTeng*. (2012/2) Identification of Escherichia coli genes associated with urinary tract infections. Journal of clinical microbiology. 50:449-456. (SCI). *Corresponding Author.


1.      Wen Teng, Pei-Chi Hou, Kuan-Der Lee, Pei-Yi Chu, Kun-TuYeh, Victor Jin, Min-Jen Tseng, Shaw-Jenq Tsai, Yu-Sun Chang, Chi-Sheng Wu, H. Sunny Sun, Kuen-daw Tsai, Long-Bin Jeng, Kenneth Nephew, Tim Huang, Shu-Huei Hsiao, and Yu-Wei Leu. (2011) Targeted Methlation of Two Tumor Suppressor Genes Is Sufficient to Transform Mesenchymal Stem Cells into Cancer Stem/Initiating Cells. Cancer Research. 71(13): 4653- 4663.

2.      Chia-Chen Hsu, Yu-Wei Leu, Min-Jen Tseng, Kuan-Der Lee, Tzen-Yu Kuo, Jia-Yi Yen, Yen-Ling Lai, Yi-Chen Hung, Wei-Sheng Sun, Pei-Yi Chu, Chien-Min Chen, Kun-TuYeh, Pearlly S. Yan, H. Sunny Sun, Yu-Sun Chang, Tim H.-M. Huang, and Shu-Huei Hsiao (2011) Functional characterization of Trip10 in cancer cell growth and survival. Journal of Biomedical Science. 18:12.

3.      Ying-Fan Chen, Chao-Ling Tung, Wen-Chi Hsiao, Yao Chang,lh-Jen Su and H. Sunny Sun*. (2011) Analysis of global methylation using a Zta­expressing nasopharyngeal carcinoma cell line. Genomics. 97(4):205-13.

4.      San-Yuan Huang, Jyh-Hung Lin, Shih-HuaTeng, H. Sunny Sun, Yu-Hui Chen, Meng-Ting Chung, Chin-kai Chuang, En-Chung Lin, and Mu-Chiou Huang. (2011) Differential expression of porcine testis proteins during postnatal development.Animal Reproduction Science. 123(3-4):221-33.

5.      Bing-Huang Gau, Tsung-Ming Chen, Yu-Herg J. Shih, and H. Sunny Sun*. (2011) FUBP3 interacts with FGF9 3' microsatellite and positively regulates FGF9 translation. Nucleic Acids Res. 39(9):3582-93.

6.      Chang N-S (2011) Solanumincanum extract (SR-T100) induces human cutaneous squamous cell carcinoma apoptosis through modulating tumor necrosis factor receptor signaling pathway. Journal of dermatological science. Vol. 63, No. 2, 83-92.

7.      Lin HP,Chang JY, Huang SS, Lin SR, Lee MH, Hsu LJ, Chang N-S (2011, May) Identification of an in vivo MEK/WOX1 complex as a master switch for apoptosis in T cell leukemia. Genes & Cancer. 2(5): 550–562.doi:10.1177/1947601911418498

8.      Lin HP, Chang JY, Huang  SS, Lin SR, Lee MH, Hsu LJ, Chang N-S (2011) Phorbol ester dissociates an in vivo MEK/WOX1 complex for switching on a novel type of apoptosis in T lymphocytes. Genes & Cancer. 2:550-562.

9.      Wu CH, Liang CH, Shiu LY, Chang LC, Lin TS, Lan CC, Tsai JC, Wong TW, Wei KJ, Lin TK, Chang N-S, Sheu HM (2011) Solanumincanum extract (SR-T100) induces human cutaneous squamous cell carcinoma apoptosis through modulating tumor necrosis factor receptor signaling pathway. J. Deramtolog. Sci. 63, 83-92.

10.  Lee JW, Liao P-C, Young K-C, Chang CL, Chen SSL, Chang TT, Lai M-D and Wang S-W. (2011) Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature Hepatitis C virus core protein. J Proteome Res 10:4522-34.

11.  Chiang C. W., Liu W. K., Chou C. K. (co-corresponding). (2011) Phosphorylation-dependent association of the G4-1/G5PR regulatory subunit with IKKβ negatively modulates NF-κB activation through recruitment of protein phosphatase 5. Biochem J. 433(1):187-96.

12.  Hsu C. C., Chiang C. W., Cheng H. C., Chang W. T., Chou C. Y., Tsai H. W., Lee C. T., Wu Z. H., Lee T. Y., Chao A, Chow N. H., Ho C. L. (2011) Identifying LRRC16B as an oncofetal gene with transforming enhancing capability using a combined bioinformatics and experimental approach. Oncogene. 30 (6):654-667

13.  Chen JY, Tang YA, Huang SM, Juan HF, Wu LW, Sun YC, Wang SC, Wu KW, Balraj G, Chang TT, Li WS, Cheng HC, and Wang YC. (2011) A novel sialyltransferase inhibitor suppresses FAK/paxillin and angiogenesis signaling and cancer metastasis. Cancer Research. 71:473-83.

14.  Tsai WC, Lin YC, Tsai ST, Shen WH, Chao TL, Lee SL, and Wu LW. (2011) Lack of modulatory function of coding nucleotide polymorphism S100A2_185G>A in oral squamous cell carcinoma. Oral Diseases. 17:283-290.

15.  Yeh CH, Tsai SH, Wu LW (co-corresponder), and Lin YC. (2011) Using co-culture microsystem for cell migration under fluid shear stress. Lab Chip. 11:2583-90.

16.  Wu, A. B., M. C. Wang, C. C. Tseng, W. H. Lin, Ching-HaoTeng, A. H. Huang, K. H. Hung, C. Chiang-Ni, and J. J. Wu. (2011/8) Clinical and microbiological characteristics of community-acquired Staphylococcus lugdunensis infections in southern Taiwan. Journal of clinical microbiology 49:3015-3018. (SCI)

17.  S. M. Faisal, J. W. Chen, S. P. McDonough, C. F. Chang, Ching-HaoTeng, and Y. F. Chang. (2011/3) Immunostimulatory and antigen delivery properties of liposomes made up of total polar lipids from non-pathogenic bacteria leads to efficient induction of both innate and adaptive immune responses. Vaccine. 29:2381-2391. (SCI)

18.  Yeh MT, Wang SW, Yu CK, Lin KH, Lei HY, Su IJ, Wang JR. (2011) A single nucleotide in stem loop II of 5'-untranslated region contributes to virulence of enterovirus 71 in mice. PLOS One. 6(11):e27082.

19.  Sun HY, Ou NY, Wang SW, Liu WC, Cheng TF, Shr SJ, Sun KT, Chang TT, Young KC. (2011) Novel Nucleotide and Amino Acid Covariation between the 5'UTR and the NS2/NS3 proteins of Hepatitis C Virus: Bioinformatic and Functional Analyses. PLOS One. 6(9):e25530. .

20.  Yang ML, Chen YH, Wang SW, Huang YJ, Leu CH, Yeh NC, Chu CY, Lin CC, Shieh GS, Chen YL, Wang JR, Wang CH, Wu CL, Shiau AL. (2011, Oct) Galectin-1 binds to influenza virus and ameliorates influenza virus pathogenesis. J Virol.85(19):10010-20.

21.  Ko, N. Y., H. C. Lee, C. C. Hung, F. C. Tseng, J. L. Chang, N. Y. Lee, C. M. Chang, M. P. Lee, B. J. Chen, S. W. Wang, and W. C. Ko. (2011) Trends of HIV and sexually transmitted infections, estimated HIV incidence, and risky sexual behaviors among gay bathhouse attendees in Taiwan: 2004-2008. AIDS Behav. 15:292-297.

22. Manrique, M., P. A. Kozlowski, A. Cobo-Molinos, S. W. Wang, R. L. Wilson, D. C. Montefiori, K. G. Mansfield, A. Carville, and A. Aldovini. (2011) Long-Term Control of Simian Immunodeficiency Virusmac251 Viremia to Undetectable Levels in Half of Infected Female Rhesus Macaques Nasally Vaccinated with Simian Immunodeficiency Virus DNA/Recombinant Modified Vaccinia Virus Ankara. J Immunol 186:3581-3593.


1.      Chang CL, Chan KH, Ma LJ, Larry Paris,Renn-Shiuan Wei and Tan CY. (April 15, 2010) Alterations of NDP kinase A /NM23-H1 deregulate c-myc transcription. Volume 70, Issue 8, Supplement 1  doi: 10.1158/1538-7445

2.      Tsung-Ming Chen, Chien-Hui Hsu, Shaw-Jenq Tsai, and H. Sunny Sun*. (2010) AUF1 p42 isoform selectively controls both steady-state and PGE2-induced FGF9 mRNA decay. Nucleic Acids Res. 38(22):8061-8071.

3.      Shu-Huei Hsiao; Kuan-Der Lee; Chia-Chen Hsu; Min-Jen Tseng; Victor Jin; Wei-Sheng Sun; Yi-Chen Hung; Kun-TuYeh; Pearlly Yan; Yen-Yu Lai; H. Sunny Sun; Yen-Jung Lu; Yu-Sun Chang; Shaw-Jenq Tsai; Tim Huang, and Yu-Wei Leu. (2010) DNA methylation of the Trip10 promoter accelerates mesenchymal stem cell lineage determination. BiochemBiophys Res Commun. 24:400(3):305-12.

4.      Tzu-Ling Tseng, Wei-Chung Lai, Ting Jian, Chuan Li, Hsiao-Fang S. Sun,Tzong-Der Way, Jia-ChingShieh, (2010) Affinity purification of Candida albicans CaCdc4-associated proteins reveals the presence of novel proteins involved in morphogenesis. BiochemBiophys Res Commun. 23:395(1):152-7.

5.      Lin YM, Tsai CC, Chung CL, Chen PR, Sunny Sun H, Tsai SJ, Huang BM. (2010) Fibroblast growth factor 9 stimulates steroidogenesis in postnatal Leydig cells. Int J Androl. 33(3):545-53.

6.      Chang N-SChang JY, Sze CI, Hong Q, Hsu LJ, Kuo YM, Chiang MF, Lee MH, Lin SR, Gong CX (2010) TTGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease. Cell Death & Disease. 1(12):e110.

7.      Lee MH, Lin SR, Chang JY, Schultz L, Heath J, Hsu LJ, Kuo YM, Hong Q, Chiang MF, Gong CX, Sze CI, Chang NS. (2010 Dec) TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease. Cell Death Dis. 23:1(12):e110.

8.      Dudekula S, Lee MH, Hsu LJ, Chen SJ, Chang NS. (2010 Dec) Zfra is a small wizard in the mitochondrial apoptosis. Aging (Albany NY). 2(12):1023-9.

9.      Su YD, Chiu KC, Chang NS, Wu HL, Chen SJ. (2010 Sep) Study of cell-biosubstrate contacts via surface plasmonpolariton phase microscopy. Opt Express. 13:18(19):20125-35. doi: 10.1364/OE.18.020125.

10.  Chang JY, He RY, Lin HP, Hsu LJ, Lai FJ, Hong Q, Chen SJ, Chang NS. (2010 Jul) Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase. ExpBiol Med (Maywood). 235(7):796-804.

11.  He RY, Su YD, Chiu KC, Chang N-S, Wu HL, Chen SJ (2010) Imaging live cell membranes via surface plasmon-enhanced fluorescence and phase microscopy. Optics Express. 18:649-3659.

12.  Chang HH, Lee H, Hu MK, Tsao PN, Juan JF, Huang MC, Shih YY, Wang BJ, Jeng YM, Chang CL, Huang SF, Tsay YG, Hsieh FJ, Lin KH, Hsu WM and Liao YF. (2010) Notch1 expression predicts an un-favorable prognosis and serves as a therapeutic target of patients with neuroblastoma. Clin Cancer Res. 16: 4411-4420.

13.  Lee T. Y., Lai T. Y., Lin S. C., Wu C. W., Ni I. F., Yang Y. S., Hung L. Y., Law B. K., and Chiang C. W. (2010, July) The B56γ3 Regulatory Subunit of Protein Phosphatase 2A(PP2A) Regulates S Phase-specific Nuclear Accumulation of PP2A and the G1 to S Transition. J. Biol. Chem. 285 (28): 21567-21580

14.  Chen S. H., Wang Y. W., Hsu J. L., Chang H. Y., Wang C. Y., Shen P. T., Chiang C. W., Chuang J. J., Tsai H. W., Gu P. W., Chang F. C., Liu H. S., Chow N. H. (2010) Nucleophosmin in the pathogenesis of arsenic-related bladder carcinogenesis revealed by quantitative proteomics. Toxicol.Appl. Pharmacol. 242:126-135

15.  Kao YC, Wu LW, Shi CS, Chu CH, Huang CW, Kuo CP, Sheu HM, Shi GY, and Wu HL. (2010) Down-regulation of thrombomodulin, a novel target of Snail, induces tumorigenesis through epithelial-mesenchymal transition. Molecular and Cellular Biology. 30:4767-85.

16.  Tsai ST, Chien IH, Shen WH, Kuo YZ, Jin YT, Wong TY, Hsiao JR, Wang HP, Shih NY, Wu LW. (2010) ENO1, a potentialprognostic head and neck cancer marker, promotes transformation partly via chemokine CCL20 induction.  European Journal of  Cancer. 46:1712-23.

17.  Pan SC, Wu LW (co-corresponder), Chen CL, Shieh SJ, Chiu HY. (2010) Deep partial thickness burn blister fluid promotes neovascularization in the early stage of burn wound healing. Wound Repair Regeneration. 18:311-8.

18.  He MF, Huang YH, Wu LW (co-corresponder), Ge W, Shaw PC, and But PPH.  (2010) Triptolide functions as a potent angiogenesis inhibitor. International Journal of Cancer. 126:266-278.

19.  Sun YN, Wang YY, Chang SC, Wu LW and Tsai ST.  (2010)  Color-based tissue segmentation for the automated estimation of oral cancer parameters.  Microscopy Research and Technique. 73:5-13.

20.  J. Scaria, L. D. Warnick, J.B. Kaneene, K. May, Ching-HaoTeng, and Y. F. Chang. (2010/12) Comparison of phenotypic and genotypic antimicrobial profiles in Escherichia coli and Salmonella enterica from the same dairy cattle farms. Molecular and Cellular Probes. 24:325-45. (SCI)

21.  Ching-HaoTeng, Y. T. Tseng, R. Maruvada, D. Pearce, Y. Xie, M. Paul-Satyaseela, and K. S. Kim. (2010/7) NlpI contributes to Escherichia coli K1 strain RS218 interaction with human brain microvascular endothelial cells. Infection and immunity. 78:3090-3096. (SCI)

22. C. S. Chiou, H. Y. Li, S. K. Tung, C. Y. Chen, Ching-HaoTeng, J. C. Shu, J. T. Tseng, C. Y. Hsu, and C. C. Chen. (2010/6) Identification of prophage gene z2389 in Escherichia coli EDL933 encoding a DNA cytosine methyltransferase for full protection of NotI sites. International journal of medical microbiology. 300: 296-303. (SCI)


1.      Lin, Yi-Mei J., Huei-Chen Ko, Fong-Ming Chang, Tzung-LiehYeh, and H. Sunny Sun*. (2009) Population-specific functional variant of the TPH2 gene 2755C>A polymorphism contributes risk association to major depression and anxiety in Chinese peripartum women. Arch WomensMent Health. 12(6):401–408.

2.      He RY, Chang CH, KC, Chang N-S, Su YD, Chen SJ (2009) Surface plasmon-enhanced two-photon fluorescence microscopy for live cell membrane imaging. Optics Express. 17: 5987-5997.

3.      Hong Q, Sze CI, Lin SR, Lee MH, He RY, Schultz L, Chang JY, Chen SJ, Boackle RJ, Hsu LJ, Chang NS (2009) Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells. PLoS ONE. 4:e5755.

4.      Lee MH, Lin SR, Chang N-S (2009) TGF-β1-induced TIAF1 self-association leads to apoptosis. In New Trends in Alzheimer & Parkinson Related Diseases: ADPD 2009, Editors A. Fisher & I. Hanin, Medimond International Proceedings. pp. 149-155.

5.      Li MY, Lai FJ, Hsu LJ, Lo CP, Cheng CL, Lin SR, Lee MH, Chang JY, Subhan D, Tsai MS, Sze CI, Pugazhenthi S, Chang NS*, Chen ST. (2009) Dramatic Co-Activation of WWOX/WOX1 with CREB and NF-kappaB in Delayed Loss of Small Dorsal Root Ganglion Neurons upon Sciatic Nerve Transection in Rats. PLoS One 4, e7820.

6.      Hsu LJ, Schultz L, Hong Q, Van Moer K, Heath J, Li MY, Lai FJ, Lin SR, Lee MH, Lo CP, Lin YS, Chen ST, Chang NS. (2009) Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1. J. Biol.Chem284:16049-16059.

7.      Yang JC, Deng CF, Wu HC, Chuang HC, Tsai TF, Hsu HY, Huang WY, Wu LW, and Su IJ. (2009) Enhanced Expression of Vascular Endothelial Growth Factor-A in Ground Glass Hepatocytes and Its Implication for Hepatitis B Virus-related Hepatocarcinogenesis. Hepatology. 49:1962-1971.

8.      Lo IC, Lin TM, Chou LH, Liu SL, Wu LW, Shi GY, Wu HL, Jiang MJ. (2009) Ets-1 mediates platelet-derived growth factor-bb-induced thrombomodulin expression in human vascular smooth muscle cells. Cardiovascular Research 81(4):771-779.

9.      He MF, Liu L, Ge W, Shaw PC, Jiang R, Wu LW, and But PPH. (2009) Antiangiogenic activity of Tripterygiumwilfordii and its terpenoids. Journal of Ethnopharmacology. 121:61-8.

10.  Lin, Y. W., S. W. Wang, Y. Y. Tung, and S. H. Chen. (2009) Enterovirus 71 infection of human dendritic cells. ExpBiol Med (Maywood). 234:1166-1173.

11.  Su, H. W., S. W. Wang, F. K. Ghishan, P. R. Kiela, and M. J. Tang. (2009) Cell confluency-induced Stat3 activation regulates NHE3 expression by recruiting Sp1 and Sp3 to the proximal NHE3 promoter region during epithelial dome formation. Am J Physiol Cell Physiol. 296:C13-24.

12. Manrique, M., P. A. Kozlowski, S. W. Wang, R. L. Wilson, E. Micewicz, D. C. Montefiori, K. G. Mansfield, A. Carville, and A. Aldovini. (2009) Nasal DNA-MVA SIV vaccination provides more significant protection from progression to AIDS than a similar intramuscular vaccination. Mucosal Immunol2:536-550.

  1. Hsu LJ, Hong Q, Schultz L, Kuo E, Lin SR, Lee MH, Lin YS, Chang N-S (2008) Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria. Cell. Signal. 20:1303-1312.
  2. Lo CP, Hsu LJ, Li MY, Hsu SY, Chuang JI, Tsai MS, Lin SR, Chang N-S, Chen ST (2008) MPP+ -induced neuronal death in rats involves tyrosine 33 phosphorylation of WW domain-containing oxidoreductase WOX1. Euro. J. Neurosci27:1634-1646.
  3. Chiang C.W., Yan L., Yang E. (2008) Phosphatases and regulation of cell death. Methods in Enzymology. 446:237-257
  4. Kuo Y. C., Huang K. Y., Yang C. H., Yang Y. S., Lee W. Y. and Chiang C. W. (2008) Regulation of Phosphorylation of Thr-308 of Akt, Cell Proliferation, and Survival by the B55α Regulatory Subunit Targeting of the Protein Phosphatase 2A Holoenzyme to Akt, J Biol. Chem. 283(4):1882-1892.
  5. Chen YH, Huang YH, Wu HL, Wu MP, Kuo YZ, Chang WT, Lu KC and Wu LW. (2008) Angiostatin K1-3 induces E-selectin via AP1 and Ets1: a mediator for anti-angiogenic action of K1-3. Journal of Thrombosis and Haemostasis. 6: 1953-1961.
  6. Wu MP, Young MJ, Tzeng CC, Tzeng CR, Huang KF, Wu LW (co-coresponder), Chou CY. (2008) A novel role of thrombospondin-1 in cervical carcinogenesis:Inhibit stroma reaction by inhibiting activated fibroblasts from invading cancer. Carcinogenesis. 29: 1115-23.
  7. Hu HT, Huang YH, Chang YA, Lee CK, Jiang MJ, and Wu LW. (2008)  Tie2-R849W mutant in venous malformations chronically activates a functional STAT1 to modulate gene expression. J. Invest. Dermatol. 128:2325-33.
  8. Y. Xie, G. Parthasarathy, F. Di Cello, Ching-Hao Teng, M. Paul-Satyaseela, and K. S. Kim. (2008/1). Transcriptome of Escherichia coli K1 bound to human brain microvascular endothelial cells. Biochemical and biophysical research communications. 365:201-206. (SCI)
  9. Wang, H. C., S. W. Huang, S. W. Wang, H. P. Tsai, D. Kiang, S. M. Wang, C. C. Liu, I. J. Su, and J. R. Wang. (2008) Co-circulating genetically divergent A2 human metapneumovirus strains among children in southern Taiwan. Arch Virol. 153:2207-2213.
  10. Manrique, M., E. Micewicz, P. A. Kozlowski, S. W. Wang, D. Aurora, R. L. Wilson, M. Ghebremichael, G. Mazzara, D. Montefiori, A. Carville, K. G. Mansfield, and A. Aldovini. (2008) DNA-MVA vaccine protection after X4 SHIV challenge in macaques correlates with day-of-challenge antiviral CD4+ cell-mediated immunity levels and postchallenge preservation of CD4+ T cell memory. AIDS Res Hum Retroviruses 24:505-519.
  1. Hong Q, Hsu LJ, Schultz L, Pratt N, Mattison J, Chang N-S (2007) Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response. BMC Mol. Biol8:50 (cited by Nature Rev Mol Cell Biol 5,378, 2008; Nature Chem Biol 5,313, 2008)
  2. Chang N-S, Hsu LJ, Lai FJ, Sheu HM, Lin YS (2007) WW domain-containing oxidoreductase: tumor suppressor, promoter, or both? Trends in Mol. Med13:12-22. (Invited review)
  3. Hong Q, Kuo E, Schultz L, Boackle RJ, Chang N-S (2007) Conformationally altered hyaluronan restricts complement classical pathway activation by binding to C1q, C1r, C1s, C2, C5 and C9, and suppresses WOX1 expression in prostate DU145 cells. Int. J. Mol Med. 19:173-179.
  4. Wang Q. F., Chiang C. W., Wu C. C., Cheng C. C., Hsieh S. J., Chen J. C., Hsieh Y. C., Hsu S. L. (2007) Gypenosides induce apoptosis in human hepatoma Huh-7 cells through a calcium/reactive oxygen species-dependent mitochondrial pathway. Planta Med. 73(6):535-44.
  5. Lin C. F., Chen C. L., Chiang C. W., Jan M. S., Huang W. C. and Lin Y. S. (2007 Aug) GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis.J Cell Sci. 15;120(Pt 16):2935-43.
  6. Wu LW, Chiang YM, Chuang HC, Lo CP, Yang KY, Wang SY, Shyur LF. (2007) A novel polyacetylene significantly inhibits angiogenesis and promotes apoptosis in human endothelial cells through activation of the CDK inhibitors and caspase-7. Planta Medica. 73:655-61.
  7. Su, H. W., H. H. Yeh, S. W. Wang, M. R. Shen, T. L. Chen, P. R. Kiela, F. K. Ghishan, and M. J. Tang. (2007) Cell confluence-induced activation of signal transducer and activator of transcription-3 (Stat3) triggers epithelial dome formation via augmentation of sodium hydrogen exchanger-3 (NHE3) expression. J Biol Chem 282:9883-9894. SCI: Imapct factor 4.773, Ranking 66/289
  1. Chen, C. L, Lin, C. F., Chiang, C. W., Jan, M. S. and Lin, Y. S. (2006) Lithium Inhibits Ceramide- and Etoposide-induced PP2A Methylation, Bcl-2 Dephosphorylation, Caspase-2 Activation and Apoptosis. Molecular Pharmacology. 70(2):510-517.
  2. Chen Y. H., Wu H. L., Li C., Huang Y. H., Chiang C. W., Wu M. P., Wu L. W. (2006) Anti-angiogenesis mediated by angiostatin K1-3, K1-4 and K1-4.5. Involvement of p53, FasL, AKT and mRNA deregulation. Thromb Haemost. 95:668-677
  3. Tsai WC, Tsai ST, Jin YT, and Wu LW. (2006) Cyclooxygenase 2 is involved in S100A2-mediated tumor suppression in squamous cell carcinoma. Mol Cancer Res. 4:539-547.
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