實驗室

分機5592
 
個人資料
 
研究成果
 

其他

 

張南山特聘教授兼任所長 (Nan-Shan Chang)

E-mail:changns@mail.ncku.edu.tw

電話:06-2353535 分機5268

傳真:06-2095845

 

學經歷

 

學歷

1974/9-1978/6

國立台灣師範大學,學士

 

1980/8-1984/12

美國南卡羅萊納大學基礎與臨床微生物與免疫學博士

   

 

現職

2010/08~

國立成功大學醫學院分子醫學研究所所長

 

2006/09~

國立成功大學醫學院分子醫學研究所特聘教授

 

1991/01~

Consultant, GlycoMed Research Incorporated, Hastings on Hudson, NY

 

1989/09~

Adjunct Associate Professor, Medical University of South Carolina, College of Dental Medicine

 
 
經歷 1995/7~2005/12 Associate Scientist and Laboratory Director, Guthrie Research Institute, Laboratory of Molecular Immunology & Protein/Peptide Microsequencing Core Facility
  1989/7~1995/6 Assistant Scientist and Laboratory Director, Guthrie Research Institute, Laboratory of Molecular Immunology & Protein/Peptide Microsequencing Core Facility
  1996/3-2006/8 Adjunct Research Associate Professor, Upstate Medical University at Syracuse, Department of Immunology and Microbiology & Integrated Medicine
  1987/1-1989/6 Instructor, University of Massachusetts Medical Center, Department of Biochemistry
  1985/1-1986/12 Post Doctoral Fellow, The Samuel Roberts Noble Foundation, Immunology Section
  1982 Teaching Assistant of Dental Microbiology for one semester, Medical Univ. of South Carolina, Dept. of Basic & Clinical Immunology & Microbiology
  1978/7-1980/7 Teaching Assistant, National Taiwan Normal Univ., Department of Biology
  1977 winter Research Assistant, Tungkang Marine Laboratory, Tungkang, Taiwan

 

專長/研究興趣

 

細胞訊息傳遞、細胞凋亡

 

1.  Mechanism of apoptosis:  Role of WW domain-containing oxidoreductase WOX1 in regulation of mitochondrial apoptosis and cancerous progression.  We discovered this gene in year 2000, and have been the leader in the field (research supported by NSC, NHRI, & Dept. Defense USA).

2.  Signaling transduction and neurodegeneration: Elucidating signaling network that controls neurodegeneration (research supported by NSC & NHRI).

3.  Naturally occurring small-size anticancer proteins: Role of Zfra in protein turnover and tumor progression (research supported by Dept. Defense USA & DOH, Taiwan).

 

榮譽獎項

 
2011 美國實驗生物醫學協會傑出科學家獎

2010

DOD Neurofibrometosis Research Award

2008

DOD Breast Cancer Concvept Award